Fertilization - 國立中興大學

Fertilization - 國立中興大學

Cleavage and implantation Day 1 ===== Day 14 http://web.nchu.edu.tw/pweb/users/chenjr/

Cleavage in mammalian zygote Morula

(cleavage patterns):cleavage patterns):): - (total or holoblastic cleavage):total or holoblastic cleavage): - (cleavage patterns): ) (cleavage patterns): ) - (total or holoblastic cleavage):partial or meroblastic cleavage): -

Mature Xenopus oocyte (total or holoblastic cleavage):total or holoblastic cleavage): -Spiral cleavage -Radial cleavage

(total or holoblastic cleavage):partial or meroblastic cleavage): -Incomplete cleavage -Superficial cleavage Cleavage in Zebra Fish

Monozygotic twin Es):trogen Proges):terone

Morula s):tage : 10-11days): : 5-9 days): Implantation types :

1. (total or holoblastic cleavage):interstitial implantation) - 2. (total or holoblastic cleavage):nidation implantation) (total or holoblastic cleavage):superficial implantation): -

(total or holoblastic cleavage):nidation) carnivores):, ruminants):, hors):es):,

and pigs): (total or holoblastic cleavage):interstitial) rats

and mice humans, and guinea pigs Inters):titial implantation :

- -Invade -Inges):tive -Diges):tive -E6 ~ E11

-Trophoblas):t -Syncytiotrophoblas):t -Cytotrophoblas):t -Inner cell mas):s): (cleavage patterns):embryoblas):t) bilaminar embryonic dis):c

Trophoblast : -Cytotrophoblas):t -Syncytiotrophoblas):t -EPF (cleavage patterns):early pregnancy factor) -24 48hr -- 10 days):

-In mothernal s):erum -hCG -10 days): -In mothers): urine Embryoblas):t (cleavage patterns):inner cell mas):s):) Hypoblas):t (cleavage patterns):primary endoderm)

hCG corpus): luteum proges):terone hCG EPF Inhibition of implantation -Diethyls):tilbes):trol -RU486

(cleavage patterns):nidation) (cleavage patterns):s):uperficial implantation) : - (total or holoblastic cleavage):apposition): - (total or holoblastic cleavage):adhension):

- (total or holoblastic cleavage):attachment):

11-12 16-17 (cleavage patterns):5) 14-17 20-21 (cleavage patterns):4-6)

8-32 40-45 (cleavage patterns):13-32) 4-16 10 16

28-35 (cleavage patterns):19-24) 5-40 38-39 95-105 (cleavage patterns):65-90) 2-13

12 13-14 16-18 24-26 (cleavage patterns):13-22) 6-7 12-13 (cleavage patterns):6)

* 1. - -

- 2. - - -

Intracytoplas):mic s):perm injection Surrogate mothers): Intracytoplas):mic s):perm injection

(ectopic pregnancies) ectopic pregnancies) Human Placenta previa Antimes):ometrial

Day 8 Inner cell mas):s): Bilaminar dis):c Hypoblas):t Epiblas):t

Amnion +EpiblastEpiblas):t Amnoitic cavity Hypoblas):t exocoelomic membrane Blas):tocytic cavity Exocoelomic cavity

(cleavage patterns):primary yolk s):ac ) Day 9 Extraembryonic mes):oderm Syncytiotrophoblas):t Lacuna

Day 10 - 12 Lacunar lacunar network Syncytiotrophoblas):t

Endomatrial s):tromal cell Decidual cell => decidual reaction Extraembryonic mes):oderm Extraembryonic coelomic s):pace

Clos):ing plug Decidual cell Day 13

Extraembryonic mes):oderm Extraembryonic coelomic s):pace extraembryonic coelom Extraembryonic s):omatic mes):oderm Extraembryonic s):planchnic mes):oderm

Chorion -Extraembryonic s):omatic mes):oderm -Cytotrophoblas):t -Syncytiotrophoblas):t Extraembryonic coelom Chorionic cavity

Day 14 Primary yolk s):ac Secondary yolk s):ac Remnant of primary yolk s):ac

Cytotrophoblas):t Primary chorionic villus): Hypoblas):t Prechordal plate

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